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Article in Press

Articles in Press

July 2017

Volume 1  Issue 1

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Case Report

Periprostetic Osteolysis After 2 Level Cervical Disc Arthroplasty Featuring Artificial Nucleus

Jacob J. Ruzevick, Theodore Wagner, Christoph P. Hofstetter*

Artificial disc cervical arthroplasties are commonly performed with favorable outcomes. Here we present a rare case of Periprostetic Osteolysis in the cervical spine of a 60 year-old man who underwent placement of a C4/5 and C5/6 M6-C cervical disc arthroplasty (Spinal Kinetics, CA, USA) in 2007 in Germany. This novel implant mimics the human disc by incorporating an artificial annulus between two titanium plates. The patient did well initially but then presented 8 years after the procedure with neck and bilateral upper extremity radiculopathy.

 

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Research Article

High-Throughput Screening of Interaction Partners for MAGE-H1 during Retinoic Acid-Induced Neural Differentiation of P19 Cells Using SILAC-Immunoprecipitation Quantitative Proteomics Approach

Yong Liu*, Yujian Chen, Shide Lin, Haiping Que, Shuguang Yang, Shaojun Liu*

MAGE-H1 might be involved in the early process of neurogenesis. However, fundamental roles of MAGE-H1 during neurogenesis still need to be further investigated. In this study, we used Stable Isotope Labeling by Amino acids in Cell culture (SILAC) -immunoprecipitation quantitative proteomics to identify interaction partners of MAGE-H1 during retinoic acid (RA)-induced neural differentiation of P19 cells, and found that 62 proteins could specifically interact with MAGE-H1. Subsequently, we performed functional annotation of the identified proteins.

 

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